Samah Abousharieha
Background
Samah joined the Tenje Lab in Sept/2020 to work on employing engineering solutions to enhance organoid model.
Short CV
- 2018 - 2019, Postdoc, The Institute of Cell-Material Sciences, Kyoto University (Japan)
- 2016 - 2018, Assistant Professor, Amman University (Jordan)
- 2015 - 2016, Postdoc, The Weizmann Institute of Science (Israel)
- 2014, Postdoc, The Hebrew University of Jerusalem (Israel)
- 2012 - 2013, Postdoc, The Ohio State University (USA)
- 2009 - 2012, Lecturer, Al-Ghad College of Medical Sciences (Saudi Arabia)
- 2009, PhD in Engineering (Major in Biochemistry) "Identification of TM9SF2 as a candidate cell surface marker common to breast carcinoma cells using in-house fabricated oligonucleotide microarrays", Okayama University (Japan)
Research Project
Mechanobiology of Organoids
Organoids are 3D-culture systems that recapitulate more complex cell-cell interactions and show higher levels of functionality compared to 2D-culture system. Starting from induced pluripotent stem cells (iPSCs), these cultures can be derived due to the ability of the iPSCs to self-organize and differentiate into in vitro three-dimensional organoids. However, organoids still lag behind in yielding reproducible and diverse cell populations. In recent work, mechanical cues have been shown to enhance the diversity of organoids.
We aim to develop devices that to promote the mechanobiology of organoids which in turn would enhance organoids as drug-testing platforms and promising material in regenerative medicine.
ADD PICTURE
Research Themes
The Biomedical Engineering Division's research is consolidated under four key research themes; precision medicine, sustainability, antimicrobial resistance and data driven life science. My research is focused on precision medicine.
Key Competences
- Biomaterials
- Induced pluripotent stem cells (iPSCs) culture
- Soft-lithography fabrication
- Mechanobiology
- Immunohistochemistry
- Cryosectioning
- Organoid culture
- Confocal microscopy
Contact
Acknowledgements
Funded by the European Union (ERC, PHOENIX, 101043985)